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To the Editor:—
In the article with this title by Dr. Theodore J. Curphey in The Journal, April 12, the death described was, in my opinion, not due to the egg but to sensitivity to the bacteria of the vaccine. Egg allergies in children produce definite skin or other evidences of sensitivities with which parents are familiar and which they delete from their diets. Even a positive skin test would not definitely establish the cause as due to egg, because this patient had been having egg without symptoms.In favor of bacterial allergy is the history of aspirin sensitivity, which, in my experience, is frequently a concomitant of bacterial sensitivity: I have seen small doses of catarrhal vaccine produce symptoms approaching the description of this fatal case, and for this reason we commence all our vaccine therapy with dilutions. For example, a supervising nurse at one of our allergy clinics
Engelsher DL. FATAL ALLERGIC REACTION DUE TO INFLUENZA VACCINE. JAMA. 1947;134(5):479. doi:10.1001/jama.1947.02880220063021