[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.166.89.187. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
June 7, 1947

PROPYLTHIOURACIL IN THYROTOXICOSIS

JAMA. 1947;134(6):555. doi:10.1001/jama.1947.02880230065022

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

To the Editor:—  The article on the use of propylthiouracil in thyrotoxicosis by Dr. William S. Reveno (The Journal, April 19, p. 1190) presented some unusual if not distressing data. Of 18 previously untreated cases, 9 were reported with initial basal metabolic rates ranging from plus 9 to plus 15 inclusive. While I am not unaware that thyrotoxicosis may occur with a metabolic rate near plus 15, such an occurrence is decidedly uncommon and should be supported by carefully documented observations. I believe the use of so potent and revolutionary a drug as propylthiouracil certainly demands more care in the selection of cases to be reported.

First Page Preview View Large
First page PDF preview
First page PDF preview
×