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June 21, 1947


Author Affiliations


From the University of Buffalo School of Medicine and the E. J. Meyer Memorial Hospital.

JAMA. 1947;134(8):662-666. doi:10.1001/jama.1947.02880250010003

In the course of a recent analysis of the effect of treatment of patients with decompensated Laennec's cirrhosis,1 we were impressed with the increasing incidence of jaundice in recent years. We are reporting our observations in order to propose some questions concerning the part that this jaundice plays in the life cycle of cirrhosis, especially of Laennec's cirrhosis.

Rolleston and McNee (1929) say: "Jaundice is not a prominent feature in portal cirrhosis, but it is met with at some time in the course of the disease in more than one third of the cases. Thus in 293 cases, obtained by combining the statistics of Fagge, Yeld and Sears and Lord, jaundice was recorded in 107, or 36.5 per cent. Eppinger estimated that it occurred in half the cases. The jaundice is usually slight and often transient. It may be merely an incident in the course of the disease, and

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