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Article
June 5, 1954

KERATOACANTHOMA

Author Affiliations

Philadelphia

From the Skin and Cancer Hospital of Philadelphia and the Department of Dermatology, School of Medicine, and Graduate School of Medicine of the University of Pennsylvania.

JAMA. 1954;155(6):562-564. doi:10.1001/jama.1954.03690240028008
Abstract

MacCormac and Scarff,1 in 1936 described a solitary skin tumor that they had observed in 10 patients and that they called "molluscum sebaceum." In 1950, Rook and Whimster2 pointed out that although this lesion was histologically suggestive of a malignant process, it was clinically benign. They used the term "keratoacanthoma," that had been proposed by Freudenthal.3 Musso and Gordon3 confirmed Rook and Whimster's observation that an untreated keratoacanthoma will regress spontaneously. Fouracres and Whittick4 and Beare5 emphasized the high incidence of this lesion. Perhaps numerous cases diagnosed as epithelioma are in reality keratoacanthoma.6 Lyon stated that British dermatologists confidently recognized the distinctive features of keratoacanthoma,7 and he, on a visit to this country, was responsible for arousing our interest in this process. Lancet has suggested6 the term "molluscum pseudocarcinomatosum" as best epitomizing the main features of this disorder. We have retained

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