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June 5, 1954


JAMA. 1954;155(6):596. doi:10.1001/jama.1954.03690240062027

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Leukemoid Reaction in Agranulocytosis.  —In the Bulletin of the Turkish Medical Society, vol. 17, no. 2, Prof. Müfide Küley of Istanbul and her associates described a case of agranulocytosis. The patient, a 61-year-old widow, had chronic arthritis that began 25 years before admission. It followed a septic sore throat. Sulfonamides, extraction of teeth, and tonsillectomy had not benefited the patient, and her condition gradually worsened. Joint deformity and inability to move developed, and arthritic pains and a slight fever persisted. On admission to the hospital, the woman was weak, anemic, and febrile and complained of pains in the joints, diarrhea, insomnia, loss of appetite, and inability to move. Her abdomen was soft and tender, and her right kidney had descended and could be easily palpated. Radiological examination revealed atony of the digestive organs.The erythrocyte count was 1,850,000; the leukocyte count was 1,400; the thrombocyte count was 147,000; the hemoglobin

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