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To the Editor:
—The value of gastroscopic examination of the stomach has been adequately emphasized. At times, however, the procedure is useless because the mucosa is obscured by bubbles generated by the air insufflation. In an attempt to counteract this difficulty, the possibility of employing compounds that decrease surface tension was considered by Dr. John Carbone, fellow in gastroenterology. It was decided to employ silicones. A tablet was produced that consisted of 10 mg. of Anti-foam A, (Dow Corning Corporation), 50 mg. of lactose, and the necessary isopropyl alcohol. This readily soluble tablet is swallowed with approximately 10 cc. of water 15 minutes before gastroscopy. It appeared that the production of vexacious bubbling was thereby decreased. The silicone tablet (available as Gastric-Nonfoam Tablets, Barnes-Hind Laboratories, Inc., 430 Post St., San Francisco) has no value in combating the viscid and copious contents of gastric retention. Gastric lavage is required in such
Dailey ME, Rider JA. SILICONE ANTIFOAM TABLET IN GASTROSCOPY. JAMA. 1954;155(9):859. doi:10.1001/jama.1954.03690270055031