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July 10, 1954


JAMA. 1954;155(11):999-1000. doi:10.1001/jama.1954.03690290049016

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The Liver in Schistosomiasis.  —The macroscopic and microscopic findings of the hepatitis due to Schistosoma mansoni were studied by Dr. L. Bogliolo of Belo Horizonte (Hospital Rio de Janeiro45:283, 1954), who observed 17 patients who died of the hepatosplenic form of schistosomiasis. Fourteen patients showed "clay pipe stem" cirrhosis of Symmers or "coarse periportal cirrhosis" of Hashem pathognomonic of the hepatosplenic form of schistosomiasis. This consists of a chronic productive granulomatous, fibrotic phlebitis involving the connective tissue surrounding the large portal branches. The hepatic lobules retain their morphological and functional individuality, and the normal architecture of the liver is preserved in spite of the marked thickening of the connective tissue framework. Two of the 17 cases had a second type of lesion seeming to correspond in part to the "diffuse bilharzial cirrhosis" of Hashem. The fibrotic inflammatory process is the same as in the aforementioned cases, but it

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