Storey and Lyons1 reported in 1951 six instances of mediastinal "tuberculoma" observed in a relatively short period of time. They expressed the opinion that this particular lesion, hitherto considered as extremely rare, was probably much commoner than the analysis of literature would suggest. Further, they felt that all isolated mediastinal tumors should be removed because some of them would prove malignant and others, even though not malignant, would eventually produce pressure symptoms on the important neighboring structures. These lesions always presented themselves as distinct tumors. An accurate diagnosis could be made only after a thoracotomy with removal or biopsy of the mass. No association with lymphadenopathy was observed in any of the reported cases. Histologically these tumors presented a characteristic picture of a chronic granuloma.
Review of the literature reveals that Grace2 in 1942 was first to report a removal of a "tuberculoma" with excellent result. Blades and
MEDIASTINAL GRANULOMA. JAMA. 1954;155(13):1160. doi:10.1001/jama.1954.03690310038009