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September 27, 1947


Author Affiliations

Baltimore, Md.

JAMA. 1947;135(4):199-206. doi:10.1001/jama.1947.02890040001001

The problem of gynecologic cancer, as represented most conspicuously by cancer of the uterus, is only one aspect of the general problem of the disease which has so long challenged the members of the medical profession. Great advances have of course been made, but the grim citadel of cancer still looms ahead, not untouched but certainly not conquered. Until the latter part of the last century the brunt of the attack had been borne by clinicians, but with the developments which flowed from Virchow's establishment of cellular pathology reinforcements then came from the ranks of the pathologists. It was not long before pathologists became familiar with those microscopic characteristics of cancer which explain its destructive clinical course. These new concepts were promptly applied by surgeons in their elaboration of the surgical attack on the disease, which had to take cognizance of such attributes of cancer as infiltration and extension, lymphatic

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