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October 7, 1950

Tumours of the Sheaths of the Peripheral Nerves (Studies on Their Structure, Histogenesis and Symptomatology)

JAMA. 1950;144(6):506. doi:10.1001/jama.1950.02920060068036

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Abstract

This monograph is concerned primarily with the microscopic morphology and the cytogenesis of the tumors of peripheral nerves. It is based on 76 tumors of peripheral nerves and a corollary study of 5 plexiform neuromas, 5 tumors of the skin from patients with neurofibromatosis and 5 amputation neuromas.

The monograph begins with a brief survey of the literature, which is followed by a brief presentation of each of the 91 cases studied. The author then discusses the microscopic appearance of the different tumors under consideration. This important section of the monograph is lacking in clarity. The presentation is confused and leaves the impression that the author himself had no clear, concise understanding of his problem. He subdivides neurinomas into three groups of questionable validity. The well tempered and qualified statement in his discussion that even though the identification of the schwannian cells is very difficult, his material would seem to

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