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Article
September 25, 1954

DIABETES INSIPIDUS, DIABETES MELLITUS, AND INSULIN RESISTANCE WITH HISTIOCYTOSIS

Author Affiliations

Miami, Fla.

JAMA. 1954;156(4):310-312. doi:10.1001/jama.1954.02950040016005
Abstract

The coexistence of diabetes insipidus and diabetes mellitus is rare. In 1931, Dr. Frank Allen and one of us (L. G. R.) presented 2 typical cases and made reference to 10 other cases reported in the literature. In the intervening years 18 additional cases have been described, and, with the case here presented, the total number is now more than 30. The history of the two diseases will not be repeated here; emphasis will rather be laid on the modern concepts of the two diseases, especially as to pathogenesis. An attempt will be made to interpret the nature and course of the illness in terms of pathology, histology, and endocrinology and in the light of advancing science. In his "Novum Organum" Francis Bacon stated that all truth must be reinterpreted from time to time in the light of newer knowledge. Thus, in 1897 the great German pathologist Senator discussed the

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