This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
To the Editor:—
I was impressed while reading the editorial "Mediastinal Granuloma" (J. A. M. A.155:1160 [July 24] 1954) with the similarity of these lesions to some I have seen in guinea pigs where the lesion is obviously thymic in origin. I was further stimulated to recall Dr. James Ewing's article "The Thymus and Its Tumors" (Surgery, Gynecology and Obstetrics22:461, 1916). Dr. Ewing described similar lesions and cited the reference of others to the condition. Drs. Kunkel, Clagett, and McDonald mentioned the possibility of thymoma in their differential diagnosis, but apparently it was not seriously considered after the lesion was seen. I feel strongly that a thymic cause should be more seriously considered for tumors of this kind.
Simmons VP. THYMUS GLAND AND TUMORS. JAMA. 1954;156(4):448. doi:10.1001/jama.1954.02950040154024