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To the Editor:—
I read with a great deal of interest your editorial in the August 5 issue of The Journal in which you comment on the anoxemia and exercise tests for coronary insufficiency. Your conclusion that "the usefulness of both tests seems to have been demonstrated" is warranted. It might be well, however, to point out that false positive exercise tests (Stein, I., and Weinstein, J.: Further Studies of the Effect of Ergonovine on the Coronary Circulation, J. Lab. & Clin. Med.36:66, 1950) are not uncommon and that "the troublesome side effects" seen with anoxemia tests have often discouraged workers from using this method for determining coronary insufficiency.Another test for coronary insufficiency has been in use for the past five years. By the intravenous injection of ergonovine maleate the clinical and electrocardiographic picture of coronary insufficiency (Stein, I.: Observations on the Action of Ergonovine on the
Stein I. ANOXEMIA AND EXERCISE TEST FOR CORONARY INSUFFICIENCY. JAMA. 1950;144(8):707. doi:10.1001/jama.1950.02920080109025