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October 23, 1954


Author Affiliations

New York

From the departments of neurology and physical medicine and rehabilitation, New York University College of Medicine.

JAMA. 1954;156(8):755-757. doi:10.1001/jama.1954.02950080003002

Multiple sclerosis is one of modern medicine's mystery diseases. Despite intensive investigation its cause and cure remain unknown. Often readily diagnosed, even by the novice in medicine, it is at times one of the most difficult conditions, even for the neurologist, to diagnose accurately. Since the disease is not a reportable one, the exact number of persons afflicted is unknown; however, it has been estimated that there are 250,000 persons with multiple sclerosis in the United States alone. Many of these represent serious nursing problems. The cost of their medical care and the loss of the patient's earning capacity and that of the member of the family charged with the primary responsibility of caring for the patient add up not only to an annual loss of millions of dollars to our economy but to untold suffering.

The clinical course of the disease has been extensively described.1 A large number

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