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October 23, 1954


Author Affiliations

1919 N. Front St., Harrisburg, Pa.

JAMA. 1954;156(8):787. doi:10.1001/jama.1954.02950080035015

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To the Editor:—  With the increased use of radioactive iodine in the diagnosis of thyroid disorders, it becomes important that those drugs that influence the iodine uptake by the thyroid gland be recognized. To the vast number of iodine-containing substances that affect this test, the name of another—benzylpenicillin-β-diethylaminoester hydriodide (Neo-Penil; Smith, Kline and French Laboratories)—should be added. The following brief case report illustrates its action.A 50-year-old woman was admitted to the Harrisburg Polyclinic Hospital on March 7, 1954, with a chief complaint of right chest pain, chills, fever, muscular aches, and nonproductive cough. She had a temperature of 99.8 F, respirations 28 per minute, and pulse 80 per minute. Physical findings of a pneumonitis in the right side were elicited and subsequently confirmed by roentgenogram. Treatment was begun with procaine penicillin. On March 10 this was cancelled and Neo-Penil, 300,000 units twice daily, begun and continued until discharge on

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