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October 23, 1954

Chemical Pathways of Metabolism

JAMA. 1954;156(8):800. doi:10.1001/jama.1954.02950080048027

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This is the first volume of a series dealing with the various intricate facets of biochemistry. Each chapter was written by an expert in the particular phase of metabolism under consideration. The thesis that pervades the book is that a closely similar pattern of chemical change is common to all forms of life. In addition to a discussion of metabolism per se with respect to fats, sterols, and carbohydrates, there are entire chapters devoted to such topics as energy levels in metabolism, enzymes, and the biosynthesis of saccharides. Both those indoctrinated in the intricacies of the "citric acid cycle" and novitiates will find a lucid discussion of the subject by Professor Krebs. The tricarboxylic acid cycle was first proposed in 1937 under the name citric acid cycle to describe the intermediary stages of oxidation of carbohydrate in pigeon breast muscle. All new substantiating evidence in support of the cycle, since

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