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To the Editor:—
The papers by Spicknall, Kurland, Carle and Terry and of Eisele, McCullough and Beal which appeared in The Journal of August 26, pages 1470 and 1473, are of particular interest to me, since they apparently contradict a previous paper by Dr. Haden and me which reported the occurrence of a high percentage of positive intradermal reactions to Brucella antigens in a group of patients with multiple sclerosis.There are several similarities and differences between the above studies and ours. There were only slight differences in the average age of patients and in the duration of their multiple sclerosis. Spicknall's patients averaged 38 years, Eisele's 36 years and ours 35.7 years of age. In Spicknall's cases the disease had been present an average of 9.5 years, in Eisele's seven years, and in ours 6.1 years. Spicknall's and Eisele's groups had an entirely different sex ratio. Our series had
Kyger ER. INTRADERMAL REACTIONS TO BRUCELLA ANTIGENS. JAMA. 1950;144(12):1022-1023. doi:10.1001/jama.1950.02920120046022