April 3, 1948


Author Affiliations

72 Westbourne Terrace, London W. 2, England.

JAMA. 1948;136(14):946. doi:10.1001/jama.1948.02890310038018

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To the Editor:—  In view of the general air of pessimism which permeates the approach to malignant exophthalmos, an attitude shared by your contributor Dr. Willard O. Thompson (THE JOURNAL, January 31, p. 314) in his recent delightful article, perhaps it is worth while briefly to record 2 cases of successful treatment.The first patient was a Royal Air Force flight sergeant pilot aged 28, who eight years before had had an operation for a large simple goiter. He was referred for increase in weight, shortness of breath, lethargy, slowing of thought and moderate exophthalmos. He presented classic features of early myxedema: a skiagram of the chest showed tracheal compression from a substernal goiter: the goitrous mass was resected and thyroid sicca (B.P.) 1/2 grain (0.03 Gm.) three times a day and Lugol's solution 5 minims (0.31 cc.) three times a day were prescribed. His general condition improved immensely: the

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