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April 3, 1948

Digitalis and Other Cardiotonic Drugs

JAMA. 1948;136(14):954. doi:10.1001/jama.1948.02890310046034

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


An excellent summary of the present day information on digitalis and related compounds is given in this small and readable book. The various components of digitalis are reviewed in detail, starting with a brief historical account of the fractions the structural chemistry, specific pharmacologic properties and clinical experiences. A number of diagrams throughout the book clearly illustrate some of the aspects of the digitalis fractions that are confusing to the average practitioner. Basic chemical reactions and structural formulas afford the reader an opportunity to see the latest developments in the field of glycosides and materially clarify parts of the text that would otherwise be of benefit only to research workers in the field of cardiology. A number of graphs demonstrate pharmacologic action in terms of energy liberation, work performance, efficiency of operation, pulse, heart volume and absorption and elimination of the various drugs. It is to be regretted that there

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