[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.163.158.163. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
February 19, 1955

LARGE-SCALE ADMINISTRATION OF VACCINES BY MEANS OF AN AUTOMATIC JET INJECTION SYRINGE

Author Affiliations

Washington, D. C.; Cleveland

JAMA. 1955;157(8):633-637. doi:10.1001/jama.1955.02950250007003
Abstract

The injection of fluid substances through the human skin by means of a small jet at high pressure was shown to be feasible nearly 20 years ago.1 Since then several types of mechanical instruments have been devised that use this principle in the administration of certain biologicals. High pressures have been obtained by means of springs, solenoids, compressed air, carbon dioxide, or small explosive charges and with nozzles of various diameters. A wide variety of materials in volumes up to 1 ml. or greater have been inoculated by jet injection, including insulin, pituitary extract (Pituitrin), sulfones, antibiotics, vitamins, and anesthetics. These are described at length in the reports of Hingson and Hughes,2 Hirsh and co-workers,3 Hughes, Jordan, and Hill,4 and Hingson and Figge.5 The studies of Batson, Wall, and Landy6 first demonstrated the feasibility of administering a vaccine (typhoid) by jet injection.

There are

First Page Preview View Large
First page PDF preview
First page PDF preview
×