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Article
July 17, 1948

PATHOLOGIC NON-NEOPLASTIC INTRACRANIAL CALCIFICATION

Author Affiliations

Rochester, Minn.

From the Section on Roentgenology, Mayo Clinic.

JAMA. 1948;137(12):1023-1031. doi:10.1001/jama.1948.02890460019004
Abstract

Ström1 in 1919 conveniently divided intracranial calcification as revealed by roentgenograms into two groups: the physiologic and the pathologic. The former group includes structures such as the pineal gland, choroid plexus, falx cerebri and pacchionian bodies which normally may exhibit varying amounts of calcium. The pathologic group includes all tumors and certain non-neoplastic lesions. Many of the latter produce clinical signs which simulate those of a cerebral neoplasm, and in the differential diagnosis roentgenographic evidence can play a most important role. Not infrequently the roentgenologist not only can exclude the presence of a tumor but by virtue of the shape, extent and distribution of shadows of calcification can predict the nature of the disease and often the cause. The table shows a practical classification of these lesions for the roentgenologist. The pathologist may disagree with such a grouping because, microscopically, the method of deposition of calcium is similar in

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