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In the first part of this book the fundamental principles of antibiotic therapy, such as mode of action, the antimicrobial spectrums, indications for the use of antibiotics, and the toxicity of antibiotics, are adequately reviewed. The major antibiotics are then discussed individually relative to their pharmacological actions, antimicrobial activity, toxicity, methods of administration, and dosage. In the latter two-thirds of the book the treatment of individual infectious processes is outlined. Special sections dealing with pediatric, urologic, ophthalmologic, dental, dermatological, otolaryngological, surgical, obstetric, and gynecologic problems, as they relate to antibiotic therapy, are presented. The manual is all inclusive and up-to-date. At times the authors are a bit forgetful; for example, on page 278, they recommend the use of antibiotics prophylactically in patients who develop asthma during a common cold or in those whose asthma is aggravated by a common cold, while on page 66 they point out correctly that, insofar
Antibiotics and Antibiotic Therapy: A Clinical Manual. JAMA. 1955;158(2):148. doi:10.1001/jama.1955.02960020054026