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May 14, 1955

Chemical Specificity In Biological Interactions

JAMA. 1955;158(2):149. doi:10.1001/jama.1955.02960020055030

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This volume is a collection of 10 papers, most of which were given as a series of seminars at Harvard University in February and March, 1952. Much of the material deals with the role that complex formation plays in this chemical specificity. Six chapters, occupying about three-fourths of the book, are used to discuss complexing or binding. The late Edwin J. Cohn discusses the specificity of metal-protein interaction; Scatchard, Hughes, Gurd, and Wilcox consider the interaction of proteins with ions and certain small molecules; Turner deals with protein-steroid bindings, chiefly from the aspect of the chemical and physical properties of the steroids; Schubert discusses the interaction of metals and small molecules and their relationship to protein-metal complexes; Coryell discusses problems in metal complex formation from a physicochemical aspect; and Schwarzenbach considers the specificity of metal complex formation. Four chapters that do not deal with complex formation but are of interest

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