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May 21, 1955


JAMA. 1955;158(3):191. doi:10.1001/jama.1955.02960030041014

It has been estimated that about 1% of all carcinomas of the breast occur in men.1 Although carcinoma of the breast in men resembles the disease in women in various respects, there are several differences. For one, carcinoma of the male breast is a disease of older men, with the average age of men being about 10 years greater than that of women. The clinical picture of cancer of the breast is more uniform in men than in women, owing to the smaller amount of adipose tissue and the subareolar location of the glandular tissue. Tumors are generally palpable on cursory examination of the male breast and are associated with nipple retraction and skin fixation. The axillary and supraclavicular lymph nodes, the lungs, and the central bony skeleton constitute the most common sites for metastasis. Histologically, cancer of the breast is indistinguishable in the sexes and tends to metastasize

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