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Article
May 28, 1955

USE OF DIOCTYL SODIUM SULFOSUCCINATE (AEROSOL O. T.) FOR SEVERE CONSTIPATION

Author Affiliations

Ann Arbor, Mich.

JAMA. 1955;158(4):261-263. doi:10.1001/jama.1955.02960040019006a
Abstract

The purpose of this communication is to direct attention to the usefulness of dioctyl sodium sulfosuccinate (Aerosol O. T.), developed some 15 years ago, in the treatment of severe fecal impaction and lesser degrees of constipation. As one of the very first of the synthetic wetting agents it was originally popularly described in Life magazine without implication of medical usefulness, and readers may recall that its remarkable properties were illustrated by the cover picture of a duck sinking in water to which a small concentration of this material had been added. The effectiveness of this material for treating constipation is consequent to its ability to allow a hard fecal mass to be penetrated by water or by mineral oils so that it becomes effectively softened. Its action thus seems to be the simple physical effect one would expect From the Department of Pediatrics, University Hospital. The food absorption studies were

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