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This volume is an excellent summary of the problem of the diagnosis of human brucellosis by an authority in Denmark. Jersild considers first diagnostic tests for brucellosis. He points out that complement-fixing antibodies in the serum may make a delayed appearance, compared with agglutinins for Brucella, and they may persist longer in the blood than agglutinins. He concludes that the agglutination test is a highly reliable diagnostic test for active disease. The complement fixation reaction is more likely to be positive in patients that have had the disease in the past. In discussing the cutaneous test, he believes that the reaction is specific, and expresses either an active or past infection. Ten per cent of the adult population in a medical ward in Copenhagen had positive reactions, whereas less than 1 per cent of children gave positive reactions. According to Jersild the cutaneous test is not a reliable means for
Diagnostiske og terapeutiske problemer ved ferris undulans. JAMA. 1948;138(10):784-785. doi:10.1001/jama.1948.02900100064028