November 6, 1948

Osteophthisis Pelvis et Femorum: Zugleich ein Beitrag Zur Frage der spontanen Rückbildung maligner Tumoren

JAMA. 1948;138(10):786. doi:10.1001/jama.1948.02900100066035

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The author presents a case of extraordinarily extensive absorption of the skeleton involving complete disappearance of the pelvis, upper two thirds of the left femur and the head and neck of the right femur. The process began in the region of the left hip in a normal 16 year old girl, progressed rapidly for three years, and then gradually slowed down until it ceased about ten or twelve years after the onset. The patient had little pain or local symptoms, remained in relatively good health, getting about on crutches and even giving birth to 2 normal babies by cesarean section. She died at the age of 49 of a carcinoma of the stomach which had given local symptoms for only about four months.

At autopsy, a scirrhous carcinoma of the stomach was found with local peritoneal and retroperitoneal spread. Metastases were found in the resorbed areas of the pelvis and

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