December 4, 1948

Diabetes Mellitus and Exercise: A Physiopathologic Study of Muscular Work in Patients with Diabetes Mellitus

JAMA. 1948;138(14):1065-1066. doi:10.1001/jama.1948.02900140057029

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This small volume translated from Danish deals with the pathologic physiology of an important subject—the effect of muscular exercise on the person with diabetes. That the work was done under the eyes of Dr. H. C. Hagedorn—discoverer of protamine zinc insulin—at the Steno Memorial Hospital in Copenhagen, Denmark, is reassuring as to its scientific worth.

First there is a historical view of the subject. After that is a description of the experimental procedures, then the results of the experiments and last a discussion of the findings in the light of their clinical aspects. Attention is called to the fact that previous observations by various workers were based on blood sugars taken at the end of exercise periods—which would not have given the same readings as those taken during the exercise. It is also pointed out that records were not made of the total work done in comparison with levels of

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