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January 1, 1949

Nouveaux traitements de l'insuffisance hépatique

JAMA. 1949;139(1):67. doi:10.1001/jama.1949.02900180069037

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This book reviews the present knowledge and current hypotheses governing the treatment and prevention of hepatic disease and hepatic failure. After a short historical review, the rationale, indications and contraindications and methods of the different forms of treatment of hepatic insufficiency are discussed. This includes high carbohydrate diet with and without injections of insulin, administration of liver extracts, bile salt therapy, administration of sulfur (especially in the form of glutathione and methionine), and the use of the various vitamins and hormones. Another part deals with the physiopathologic basis and the practical use of the therapy with the different lipotropic substances and of the oral and parenteral high protein regimen. Special emphasis is given to therapeutic results in cirrhosis. The available literature is well and critically reviewed and an extensive bibliography makes the booklet valuable to the American reader. Many of the facts presented and the conclusions reached are based on

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