March 12, 1949

Radioactive Indicators: Their Application in Biochemistry, Animal Physiology, and Pathology

JAMA. 1949;139(11):752. doi:10.1001/jama.1949.02900280068039

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According to the preface, this book was written in the Institute for Theoretical Physics of the University of Copenhagen and the Institute for Research in Organic Chemistry of the University of Stockholm; it was completed in the Donner Laboratory of the University of California. It presents the amazing array of facts that have been learned but recently by the use of radioactive tracer substances in chemistry and biology. Despite the amount, variety and newness of this information, it is presented coherently, readably and with the exactness of detail that is in the best European tradition.

The following are the larger divisions of the text: production of radioactive isotopes; list of radioactive isotopes of possible interest in tracer work; atomic interchange; applications in chemical analysis; absorption, distribution and excretion of elements; permeability of phase boundaries; turnover studies; path of intermediary reactions; skeleton metabolism; biochemistry of red corpuscles; shortcomings of radioactive indicators.

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