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To the Editor:—
Since the introduction of dimenhydrinate (dramamine†) in 1947 by G. D. Searle & Co. many uses have been found for this drug. The most phenomenal results were those in motion sickness published by Gay and Carliner. Nevertheless, its major usefulness will be evaluated differently, depending on the phase of medicine in which one is interested. This is well illustrated by the following reports: (a) E. F. Kerman successfully treated 15 patients for nausea following electric shock and also eight patients with migraine, (b) E. Brentan employed it in migraine, (c) Beeler and co-workers in radiation sickness, (d) Campbell after fenestration operations and (e) Stoecker after local anesthesia in ophthalmology. All reports show good results. However, one of the most important uses of dimenhydrinate has not been reported as yet: that is, its use for nausea and vomiting following general anesthesia.In ophthalmology it is imperative that the
Rudolph CJ, Park DD, Hamilton C. TREATMENT OF POSTANESTHESIA NAUSEA AND VOMITING. JAMA. 1950;144(15):1283. doi:10.1001/jama.1950.02920150057025