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Each of these annual reviews as it appears affords the medical reader a priceless opportunity to note the present status of some of the perennial problems of physiology and to discover new trends in research. The present volume lives up to its predecessors in these respects, and in addition contains a prefatory chapter by DuBois, Fifty Years of Physiology in America, which brings out interesting contrasts between 1900 and 1950 as regards the life of the physiological investigator. As examples of the perennial problems referred to might be mentioned the effects of cold, the existence of gastrin and the multifarious aspects of coagulation. The cause of hypothermic death is still in doubt (page 123), and the proof that gastrin exists is weak (page 209). The proposal of a new theory of coagulation (page 239) will be hailed with groans by medical students, whose minds in the past have certainly been
Annual Review of Physiology. JAMA. 1950;144(15):1318. doi:10.1001/jama.1950.02920150092035