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October 12, 1940

Dynamics of inflammation: An Inquiry Into the Mechanism of Infectious Processes

JAMA. 1940;115(15):1302. doi:10.1001/jama.1940.02810410068038

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This volume represents the recent publications of the series of Experimental Biology Monographs designed to give in monographic form the most recent researches in the biologic sciences. The author attempts to describe inflammation from the physiologic, immunologic and biochemical as well as the morphologic point of view, drawing considerably on his own investigations. Inflammation in relation to infectious processes is especially emphasized. Allergic and anaphylactic reactions are discussed with reference to their role in the fixation of antigens. Leukotoxin, a crystalline nitrogenous substance, is offered as the agent responsible for capillary permeability and the migration of leukocytes to points of injury. The context and bibliography should be of value to pathologists and bacteriologists interested in the immunologic and chemical phases of inflammation.

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