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October 19, 1940

SHOULD SOLUTION OF POSTERIOR PITUITARY BE USEDIN THE FIRST AND SECOND STAGES OF LABOR?

Author Affiliations

PHILADELPHIA

JAMA. 1940;115(16):1315-1317. doi:10.1001/jama.1940.02810420001001
Abstract

The term solution of posterior pituitary employed in this paper includes pituitrin, pitocin, infundin, thymophysin, pitanthym and all other preparations depending for their action on the oxytoxic principle of the posterior portion of the pituitary gland.

Since its discovery and introduction into medicine, much has been written about solution of posterior pituitary.1 It is a powerful drug. In addition to its oxytoxic and pressor effects, clinical hypersensitiveness has been reported occasionally.2

As the result of investigations of the Maternal Welfare Committee of the Philadelphia County Medical Society over the past nine years and of the Committee for the Study of Stillbirths of the Obstetrical Society of Philadelphia over the past three years, I have collected some data regarding the use and abuse of this uterine stimulant in the first and second stages of labor. This paper summarizes my impression of the use of the drug in normal labor,

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