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December 14, 1940


JAMA. 1940;115(24):2040-2044. doi:10.1001/jama.1940.02810500008003

Infants of mothers with diabetes mellitus show a high morbidity and mortality rate. My object in this paper is to present sixty-five consecutive infants of diabetic mothers studied during the past ten years. Such a group of infants was almost nonexistent two decades ago, before the insulin era. Women with diabetes either did not become pregnant or failed to give birth to a living child. Since the insulin era, the fecundity of the diabetic woman has greatly increased, and the juvenile diabetic patient has now reached the childbearing age. There is, therefore, an increasing number of pregnant women with diabetes mellitus and an increasing number of infants of diabetic mothers.

This group of infants has not been studied in large enough numbers to permit definite conclusions. There are sufficient data, however, to warrant certain general conceptions with regard to these infants. Miscarriages and stillbirths are most common in this group.

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