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January 27, 1951

Cell Physiology and Pharmacology

JAMA. 1951;145(4):271. doi:10.1001/jama.1951.02920220079034

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According to the author, the material in this book was culled from a series of lectures at University College, London. It is presented in an interesting, well integrated and authoritative manner, although it is perhaps regrettable that Professor Danielli did not see fit to expand certain portions of the text and document the subjects more thoroughly. His discussions on the action of drugs on cell surfaces, on permeability and on enzyme systems offer a more comprehensive (although less detailed) survey than is ordinarily found in books on this subject. The text also outlines rather fully the reasoning that must be applied to any study of drug mechanism.

Possible drug actions are discussed in terms of surface actions, alteration of membrane permeability, and enzyme inhibition. The last named of these is the least successfully dealt with and the author seems to hold an unnecessarily discouraged view on this subject. However, some

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