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March 3, 1951


Author Affiliations

New York

From the Departments of Physiology and Surgery, New York University College of Medicine.; Fellow in the Medical Sciences, National Research Council (Dr. Ladd).

JAMA. 1951;145(9):642-643. doi:10.1001/jama.1951.72920270001009

Plastic catheters of small diameter have proved valuable in this laboratory in prolonged experiments on cats and dogs in which it was necessary to have sustained or repeated access to a vein for the purpose of either administering infusions or withdrawing blood. The present study was carried out to determine whether the same material might provide a permanent easily available entry to the human venous system and thereby simplify the problem of intravenous alimentation of debilitated patients with sclerosed or collapsed peripheral veins.

Subjects for this study were unselected patients in the Third Surgical Division of Bellevue Hospital to whom no special nursing care was given. A high incidence of veins thrombosed by previous multiple venipunctures made many of these patients serious problems from the point of view of intravenous therapy.

Two types of tubing were used. Large (for no. 14 thin-walled needles)1 and small (for no. 18 thin-walled

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