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To the Editor:—
With regard to the interesting observation of Dr. Stern, who stated that "no mention of the use of vitamin C could be found in the literature," I offer the following material. In an article published in the Journal of Laboratory & Clinical Medicine (28:1082 [June] 1943) I described a condition called syringadenitis suppurativa tropicalis, which always developed as a sequel to prickly heat. Laboratory investigations gave evidence of a vitamin C depletion, and the condition responded to large doses of vitamin C (900-1,000 mg. daily). Small doses (200-300 mg.) were effective only when the hot weather subsided and perspiration decreased. It was also my conviction that a depletion of vitamin C is caused through excessive perspiration.
Reiss F. VITAMIN C AND PRICKLY HEAT. JAMA. 1951;145(10):755. doi:10.1001/jama.1951.02920280067021