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—At the National Congress of the Italian Society of Internal Medicine, Professors Melli and Bartorelli reported on essential hypertension, which was defined as a disease characterized by a rise of systolic and diastolic blood pressure, not connected with renal diseases, arteriosclerosis or any other known cause and related to an arteriolar spasm. Essential hypertension is considerably more frequent than all the other forms of hypertension combined; it has a higher mortality rate than cancer, tuberculosis and infectious diseases in general.Experimental pathology has demonstrated several ways of inducing constant increases of pressure, including production of renal ischemia, various surgical procedures on the nervous system, modifications of humoral endocrine factors and psychic factors. It is likely that the regulation of pressure and its alterations are the result of a combined action of mechanisms in direct reciprocal relation.There may be asymptomatic forms, in which no sensation may be perceived
ITALY. JAMA. 1951;146(1):56. doi:10.1001/jama.1951.03670010060024