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May 12, 1951


JAMA. 1951;146(2):212-213. doi:10.1001/jama.1951.03670020134023

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BCG Vaccination by Mouth.  —Dr. H. J. Ustvedt, who is in charge of Department IX of the Ullevaal City Hospital, Oslo, has begun to give BCG by mouth and has some interesting experiences to relate on this subject in the organ of the Norwegian Medical Association, Tidsskrift for Den Norske Laegeforening for March 1, 1951. Oral administration of BCG, as advocated by Calmette in France, has hitherto been considered inaccurate and unreliable in the Scandinavian countries. Heimbeck of Norway introduced vaccination by subcutaneous injection and Wallgren of Sweden the intracutaneous method, but the oral method has occasionally been given a trial in Norway. In 1935 Scheel succeeded in rendering 11 out of 20 students Pirquet-positive by giving them 50 mg. of BCG by mouth. At the present time the oral administration of BCG is practiced widely in Russia and on a large scale in France, and it is often preferred

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