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First Clinical Experiments with Cortisone in Ophthalmology.
— Professor Franceschetti, head of the Ophthalmic Clinic of Geneva University, studied the local applications of cortisone in diseases of the eye; he used collyrium and ointment. The collyrium was used in two concentrations: 1 per cent and 2.5 per cent, instilled usually at the rate of one drop every two or three hours for mild cases and as a maintenance dose. The ointment has a concentration of 1 per cent; the results were also very satisfactory with only the ointment (once or three times a day), but it is not as easy to use as the collyrium.From October 1950 to February 1951, Professor Franceschetti and his collaborators treated 25 patients. From the results they published it appears that the local application of cortisone is helpful in inflammatory diseases of the cornea and sclera. Remarkable results were obtained in a case of
SWITZERLAND. JAMA. 1951;146(2):213. doi:10.1001/jama.1951.03670020135024