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June 9, 1951


JAMA. 1951;146(6):577. doi:10.1001/jama.1951.03670060053019

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Vaccinal Encephalomyelitis.  —Ord. Prof. Ihsan Hilmi Alantar of Istanbul University children's department and his associate, Dr. Metine Bilger, reported an increase in postvaccinal encephalomyelitis. There were nine cases within three months; two occurred after mumps, three after influenza, two after measles, one after whooping cough and one after smallpox vaccination; two patients died. Four patients were 6, 12, 14 and 17 months old, respectively, and five were 3 to 12 years old. Though the associated infection varied, there was an obvious similarity in clinical and laboratory findings. In a 14 month old patient, a temperature of 42 C. (107.6 F.) developed 10 days after smallpox vaccination. She was admitted to the hospital in coma, having had convulsions for the previous 10 hours. The eyes had rolled upward; reflexes were brisk, and there was no stiffness of the neck. Spinal puncture produced a clear liquor. The Pandy test was positive, and

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