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June 9, 1951

The Conquest of Malaria

JAMA. 1951;146(6):605. doi:10.1001/jama.1951.03670060081030

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In this small volume, the author attempts to recall the historical struggle against malaria and to record the names of pioneers who have added most important, fundamental contributions to the knowledge and treatment of the disease. It is divided into three parts: the mosquito-malaria theory, a critical review of the basic facts in the history of cinchona, and progress in the knowledge and treatment of malaria. About three-quarters of the book is devoted to the first two parts, which are treated in a comprehensive manner. Antimalarial drugs other than cinchona derivatives are dealt with very sketchily in part 3. Chlorguanide hydrochloride ("paludrine"), which receives major attention in the last part of the book, could be more adequately discussed, and the vast amount of research carried out in the United States during World War II receives most superficial discussion. Practically no mention is made of the importance of insecticides and DDT,

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