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The fact that both adrenocorticotropic hormone and cortisone cause a remission of rheumatoid arthritis in nearly every instance in which they are employed has been most encouraging to those treating the disease. No known previous medication could be so successfully used. However, it is becoming a well-known fact that neither of these two hormone substances cure rheumatoid arthritis. They dampen without extinguishing the fire. No such spectacular results are obtained with chrysotherapy. Complete remissions in well-established cases of rheumatoid arthritis with gold treatment occur in about 20% of treated persons. The remission, if it is obtained, is much more permanent than that with the hormone preparation. Chrysotherapy will be continued in the treatment of rheumatoid arthritis because of these facts. Also if gold therapy is continued, then the various complications associated with its treatment will be encountered. The most frequent complication of gold treatment is dermatitis. The following is a
Steinberg CL, Roodenburg AI. SUCCESSFUL TREATMENT OF DERMATITIS DUE TO CHRYSOTHERAPY WITH ADRENOCORTICOTROPIC HORMONE. JAMA. 1951;146(13):1225-1226. doi:10.1001/jama.1951.63670130005012b