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The pituitary adrenocorticotropic hormone (ACTH) was originally given the generic designation of corticotrophin in 1938 by the Third International Conference on the Standardization of Hormones of the League of Nations. Recently this name was reconsidered and again approved by the World Health Organization's Subcommittee on Non-Proprietary Names of the Expert Committee on the International Pharmacopeia. The adoption of the "-trophin" suffix posed a problem because the "-tropin" ending is generally used in the United States to describe activity directed toward stimulating a specific organ. Both suffixes are derived from the Greek: "-trophos" referring to nutrition, "-tropos," to a turn. After considerable deliberation, the Council on Pharmacy and Chemistry has decided to utilize the generic designation of corticotropin for the description of the hormone in New and Nonofficial Remedies. This generic name is not only more consonant with local usage but also more descriptive of the actual hormonal effect which is
ACTH NOMENCLATURE AND STANDARDIZATION. JAMA. 1951;147(4):326-327. doi:10.1001/jama.1951.03670210038009