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Probably no other living physician—or even any physician in the future—can have the experience that Dr. Bargen has had with ulcerative colitis. This short monograph gives a critical review of his clinical experience. He has discussed adequately the diagnosis, with all its ramifications, and the complications that might ensue. The treatment has the usual method outlined for any abdominal disease that is as disabling as ulcerative colitis. Diet is an important factor. Curiously enough, however, Dr. Bargen does not rely so much on vaccine therapy now as he did in the past, and he puts special emphasis on the use of sulfonamides. His experience with antibiotics is comparable to that of others with fewer patients, but he has come to the same general conclusion as to their therapeutic value. The author recognizes that there is some value in parasympatholytic drugs and also in barbiturates.
From a surgical point of view
Chronic Ulcerative Colitis (Thrombo-Ulcerative Colitis). JAMA. 1951;147(4):354. doi:10.1001/jama.1951.03670210066028