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September 29, 1951

Ocular Toxoplasmosis

JAMA. 1951;147(5):533. doi:10.1001/jama.1951.03670220173038

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This monograph, prepared originally as a thesis for the American Ophthalmological Society, was considered important enough by the society to be issued as a special publication. It summarizes well the current knowledge on toxoplasmosis as it affects the eye. The principal involvement is retinitis or chorioretinitis, usually in the macular or perimacular region, which results chiefly from infection during intrauterine life. A positive diagnosis is to be made on the basis of clinical findings with isolation of the Toxoplasma. The author believes the complement fixation tests and methylene blue dye tests to be most reliable in arriving at a probable diagnosis.

The author reports five cases of congenital toxoplasmosis and histological findings on the second eye in a case previously reported. In experimental toxoplasmosis in rabbits there was localization of the lesion in the uveal tract when peritoneal exudate from Toxoplasma-infected mice was injected into the carotid artery. All drugs

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