Under normal conditions, the vaginal epithelium of a healthy adult is resistant to infection. However, if the vitality of the vaginal mucosa is impaired, then infection may supervene. The factors which may decrease the resistance of the normal vaginal mucosa to infection are manifold, and include trauma (from coitus, pessary, douch nozzle, and tampon), childhood, pregnancy, menopause and any number of acute infectious and chronic diseases.
The etiological agent causing the vaginitis might be any one of the large variety of micro-organisms, animal parasites, or fungi. Although rarely a cause for vaginitis, the Escherichia coli can, under certain adverse conditions, cause this disorder. Incorrect perineal hygiene is the most important contributory factor in the transference of these micro-organisms into the vagina with the production of this disease entity.1 The purpose of this paper is to present a case of Escherichia coli vaginitis and its dramatic response to aureomycin.
Schwartz JJ. AUREOMYCIN THERAPY FOR ESCHERICHIA COLI VAGINITIS. JAMA. 1951;147(7):655. doi:10.1001/jama.1951.73670240019006i