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November 24, 1951


Author Affiliations

Veterans Administration Hospital 130 W. Kingsbridge Rd., Bronx 68.

JAMA. 1951;147(13):1297. doi:10.1001/jama.1951.03670300111025

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To the Editor:  —In the Sept. 29, 1951 issue of The Journal (p. 379) appeared a brief note entitled "Resistance to Cancer," in which an excerpt was quoted from a paper by R. W. Scarff ("The Present Status of the Cancer Problem," The Practitioner, July, 1951). In this item, the statement was made that in the case of a delayed recurrence of breast carcinoma, where after the removal of a primary tumor another tumor appears in the scar after 20 years, "it seems unlikely that this can be a second tumor arising in the breast tissue and one must accept the fact that cells have remained in situ but have been kept in check."Such an assumption is not necessary, however, and, in fact, would not be consistent with our present approach to the problem of mammary carcinoma, based on current experimental data obtained on mice. According to our present

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