Sporotrichosis in its localized forms is usually readily susceptible to iodide therapy. However, when widespread involvement of many viscera exists, the therapeutic problem is difficult because of lack of specific antibiotic therapy at the present time and the often-encountered resistance of this disease to iodides.
The beneficial effect of fever therapy observed in the patient described opens possibilities of an added therapeutic resource. To our knowledge this observation has not been reported in the literature.
REPORT OF CASE
J. K., a 40-yr.-old Negro man, was first seen in consultation on the eye ward where he had been admitted on March 6, 1950, for treatment of a recurrent iridocyclitis.He presented at that time an 8 by 10 mm. moist reddish swelling of the third knuckle of the left index finger. There were three or four hard, deep-seated nodules surrounding this region and a series of linear nodules varying in size
Thomas CC, Pierce HE, Labiner GW. SPOROTRICHOSIS RESPONDING TO FEVER THERAPY. JAMA. 1951;147(14):1342-1343. doi:10.1001/jama.1951.73670310001012